Search results for "genetics [Transcriptome]"
showing 10 items of 3033 documents
TIF1γ : un gène suppresseur de tumeur dans la leucémie myélomonocytaire chronique
2011
Signalisation calcique cytosolique et nucléaire et réponses des plantes aux stimulus biotiques et abiotiques
2006
Mutation d’HSP110 dans les cancers colorectaux
2012
Un nouveau modèle murin du vieillissement de l’hématopoïèse
2014
Un nouveau modele murin du vieillissement de l’hematopoiese Ronan Quere 1,2, Jean-Noel Bastie1,2,3, Laurent Delva1,2 1 Inserm, UMR 866, faculte de medecine, universite de Bourgogne, 7 boulevard Jeanne d’Arc, 21000 Dijon, France ; 2 Labex LipSTIC, universite de Bourgogne, 21000 Dijon, France ; 3 hopital universitaire, service d’hematologie clinique, 21000 Dijon, France. ronan.quere@inserm.fr laurent.delva@u-bourgogne.fr
Evaluation of the cytotoxic effects of MEIC chemicals 31-50 on primary culture of rat hepatocytes and hepatic and non-hepatic cell lines
1997
The cytotoxicities of 20 chemicals (numbers 31–50) from the Multicenter Evaluation of In Vitro Cytotoxicity (MEIC) programme were assessed with a primary culture of rat hepatocytes and with two hepatic cell lines (Hep G2 and FaO) and one non-hepatic cell line (3T3). The cytotoxicities of the chemicals were evaluated by using the MTT test after the cells had been exposed to the chemicals for 24 hours. For a better evaluation of results, dose–response curves were mathematically linearised and cytotoxicity was expressed as IC50 values and IC10 values (the concentration causing 50% and 10% loss of cell viability, respectively). We found that all the compounds showed similar acute basal cytotox…
COVID in 2022. Clinical risk management of sars-cov-2 positive patients admitted to an internal medicine ward
2022
Brain Research Reveals Automatic Musical Memory Functions in Children
2009
Even though music has special meanings and values compared to other sounds, it is nonetheless processed in the brain via partly the same neural networks that are built to process all kinds of sounds. The development of these brain areas depends on the input: on the sounds that a child is exposed to and chooses to attend to. We present two brain research paradigms that can be used to assess the specialization of the brain for musical sounds, and show promising results with these paradigms in a group of young children who have music as their hobby.
Current insights into neutrophil homeostasis
2012
Neutrophil granulocytes represent the first immunologic barrier against invading pathogens, and neutropenia predisposes to infection. However, neutrophils may also cause significant collateral inflammatory damage. Therefore, neutrophil numbers are tightly regulated by an incompletely understood homeostatic feedback loop adjusting the marrow's supply to peripheral needs. Granulocyte colony-stimulating factor (G-CSF) is accepted to be the major determinant of neutrophil production, and G-CSF levels have, soon after its discovery, been described to be inversely correlated with neutrophil counts. A neutrophil sensor, or "neutrostat," has, therefore, been postulated. The prevailing feedback hypo…
Post-mortem enamel surface texture alteration during taphonomic processes—do experimental approaches reflect natural phenomena?
2022
Experimental approaches are often used to better understand the mechanisms behindand consequences of post-mortem alteration on proxies for diet reconstruction.Dental microwear texture analysis (DMTA) is such a dietary proxy, using dental wearfeatures in extant and extinct taxa to reconstruct feeding behaviour and mechanicalfood properties. In fossil specimens especially, DMTA can be biased by post-mortemalteration caused by mechanical or chemical alteration of the enamel surface. Herewe performed three different dental surface alteration experiments to assess the effectof common taphonomic processes by simplifying them: (1) tumbling in sedimentsuspension to simulate fluvial transport, (2) s…
Mislabeling and nomenclatorial confusion of Typhlotanais sandersi Kudinova-Pasternak, 1985 (Crustacea: Tanaidacea) and establishment of a new genus
2022
Re-examination of historical collections allowed us to resolve the taxonomic status of Typhlotanais sandersi Kudinova-Pasternak, 1985, originally described based on a single specimen from Great-Meteor Seamount. The holotype of this species was considered lost and the species redescribed based on a second specimen from the type locality by Błażewicz-Paszkowycz (2007a), who placed Ty. sandersi on a newly established genus Typhlamia. Thorough morphological analysis of Typhlamia and Typhlotanais species and recently obtained genetic data of typhlotanaids from N Atlantic and NW Pacific waters allow us to conclude that the redescription of Ty. sandersi by Błażewicz-Paszkowycz (2007a) was based on…